Iodine 131



A dangerous and short lived product of nuclear fission

Iodine 131 is a radioisotope with a very short half-life of 8.02 days, making it highly radioactive. Frequently used in small doses in thyroid cancers therapies, it is also one of the most feared fission products when accidentally released into the environment.



Radiotoxicity of iodine 131
The radioactive toxicity of iodine 131 is measured by the ‘ingestion dose conversion factor’ which allows to calculate the efficient dose resulting from the ingestion of a given activity of a radioelement.Ingested Iodine-131 is dangerous because it primarily affects the thyroid gland, a part of the body that plays a fundamental role in childhood development. For this reason, radiotoxicity varies greatly with age, with toddlers, young children and adolescents being far more sensitive to radioactive iodine than adults.
IN2P3

In medicine, iodine 131 is primarily used to study the functionning of the thyroid though it can also be employed in the treatment of hyperthyroidism as well as thyroid cancer. The first production of iodine 131 in France took place in 1949 at the Fort de Chatillon, the site of the first Zoe atomic reactor, before manufacture was transferred to the nuclear research centre at Saclay. The isotope had been used since 1942, however, in the treatment of thyroid cancer.

Though used in low doses for medical examinations, iodine 131 is an ideal tracer for use in humans. Only a few radioactive atoms need to be inserted into the bloodstream for the iodine path to be accurately monitored. The atoms integrate into molecules that eventually transform into thyroid hormones; this is particularly interesting, given that iodine attaches itself exclusively to the thyroid gland. Gamma ray scintigraphy scans can thus monitor the thyroid activity and flag up the appearance of any anomalies. In recent years, iodine 131 has been abandoned in favour of another isotope, iodine 132 – a gamma emitter with a half-life of only 13.2 hours.

Stronger doses of iodine 131 are also used in radioactive therapies aimed at dealing with thyroid cancers. Iodine is inserted into the bloodstream in the same manner, and the short trajectory of the emitted beta particles guarantees that the radiation only affects a comparatively small part of the body.

Iodine 131 is also a feared fission product, posing as it does the principal risk for short-term contamination in the event of accidental waste release. From a chemical point of view, iodine is a halogen (similar in structure to chlorine and fluorine) and its high volatility means that it easily transforms into a purple vapour.

In any case, the high radioactivity of iodine 131 is somewhat offset by its high decay rate, with the level of activity dropping by a factor of 2,000 every two months. There are also procedures for us to protect ourselves from it before it decays.

Iodine 129, another isotope of iodine, is one of the long-lived fission products that also have to be taken into account when dealing with radioactive waste. The half-life of iodine 129 is of 15.7 million years.

Access to page in french

Related topics :Uranium 238 and 235, Plutonium-239, Radium, Carbon-14, Potassium-40, Technetium-99, Caesium-137, Tritium